Duke vs Arizona Odds, Player Props & Predictions (Nov 22)

• The #12 Duke Blue Devils visit the #17 Arizona Wildcats in Tucson on Friday night
• Both teams will be eager to avoid their second loss of the young season
• See the Duke vs Arizona odds, player props, and predictions for Nov. 22

A heavyweight Big Ten/ACC clash highlights Friday’s college basketball slate as the #12 Duke Blue Devils (3-1, 0-0 away, 3-1 ATS) visit the #17 Arizona Wildcats (2-1, 2-0 home, 1-2 ATS) at McKale Memorial Center in Tucson at 7:30 pm PT/10:30 pm ET. Both teams are already 0-1 against top-50 teams and will be keen to avoid a second setback so early in the season.

Duke vs Arizona Odds

The Wildcats are slight home favorites over the Blue Devils in Friday’s college basketball odds, sitting at -1.5 against the spread and -125 on the moneyline. Duke comes back as a +105 underdog to win straight-up.

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The Blue Devils suffered their first loss of the season last Tuesday, falling 77-72 to Kentucky as 5.5-point neutral-court favorites in Atlanta. The nation’s #1 freshman recruit Cooper Flagg, who’s already as short as +320 in the Wooden Award odds, had 26 points, 11 rebounds, two assists, and two blocks in a losing effort.

Duke’s three-point shooting – or lack thereof – was the difference in the game. The Blue Devils were just 4-of-16 from three while UK was 10-of-25.

Duke responded with a savage 86-35 beatdown of 164th-rated Wofford on Saturday. The Blue Devils opened the game on a ludicrous 36-5 run and never looked back.

Flagg was more of a distributor against the Terriers, finishing with eight points, nine rebounds, and six dimes while four of his teammates finished in double-figures, led by a team-high 15 from junior guard Tyrese Proctor.

Arizona was knocked from the ranks of the unbeaten by Wisconsin a week ago, falling 103-88 in a true road game in Madison as 4.5-point road chalk. Junior guard Jaden Bradley had a team-high 22 in the loss while the Wildcat defense was absolutely shredded for 41 points by Wisconsin’s John Tonje.

Arizona opened the season with a 93-64 home victory over Canisius (#356 at KenPom) and a 102-33 home win over Old Dominion (#311).

DUKE vs ZONA Player Props

Player props from FanDuel on Nov. 22. See SBD’s list of the best online sportsbook for payouts. 

Flagg has the highest point total of the night in the Duke/Arizona player props at 16.5 O/U while senior guard Caleb Love leads the Wildcats at 14.5 O/U. Flagg and Arizona forward Tobe Awaka have the highest rebound total on the board at 7.5.

Duke vs Arizona Predictions

This will be a difficult road environment for the young-ish Blue Devils, but they are a significantly better team on paper. Not only do they sit 13 spots higher than Arizona at KenPom (4th vs 17th), there’s an even bigger gap between the teams at Haslametrics (4th vs 19th). Both sites, along with BartTorvik.com, project a close Duke victory (with Arizona’s home-court advantage taken into account).

I also expect a bounce-back offensive performance from Flagg. He showed up big the first time Duke was in the national spotlight against Kentucky, and he’s likely to do so again tonight in Tucson, consolidating his status as the Wooden Award favorite and projected #1 pick in the NBA draft.

Duke vs Zona picks:

• Duke moneyline (+105) at ESPN Bet
• Flagg over 16.5 points (-120) at FanDuel

Sascha Paruk’s 2024-25 NCAAM betting record: 3-1 (+1.51 units). All wagers one unit unless expressly stated otherwise.