Ole Miss vs LSU Odds, Spread & Prediction – College Football Week 7

• #13 LSU hosts #9 Ole Miss in a Top 15 SEC matchup on Saturday, October 12
• LSU has won six of the last eight meetings between programs
• See below for the latest Ole Miss vs LSU odds, predictions, and picks for College Football Week 7

In one of three matchups between Top 25 teams in Week 7 of college football, Ole Miss travels to Death Valley to face LSU. Kickoff is scheduled from Baton Rouge, LA at 7:30 pm ET.

Ole Miss defeated LSU last season 55-49, but LSU has otherwise dominated this series. The Tigers have won ten of the last 14 games between these two SEC programs.

This game will likely have playoff implications, as a win for either team will go a long way in making it to the inaugural 12-team CFP bracket. Both of these teams are in the top 12 when it comes to CFP National Championship odds. Ole Miss has the sixth-best odds at +1800, and LSU has the 12th-best odds at +5000.

Keep reading to see the latest Ole Miss vs LSU odds, spread, and predictions for Saturday’s CFB Week 7 action.

Ole Miss vs LSU Odds

The college football odds list Ole Miss as a 3.5-point road favorite vs LSU. This line has held at 3.5 since opening. With -170 odds on the moneyline, the sportsbooks are giving the Rebels a 62.96% implied win probability.

Points are expected to come in bunches with a high O/U of 62. The total opened at 64 before moving down to where it is at currently. At least 62 points were scored in five of the last seven games between Ole Miss and LSU.

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Odds as of October 11 at Fanatics Sportsbook. Check out the best Fanatics Sportsbook promo code before locking in your Ole Miss vs LSU bets.

Ole Miss Betting Trends

Ole Miss is 5-1 straight up and against the spread to start their season. Led by Lane Kiffin and Jaxson Dart, the Rebels have a high-powered offense that is averaging 44 points per game. Their offense has been slowed down in SEC play, however. They scored just 17 in their loss to Kentucky and put up 27 against South Carolina last week. The over is also just 1-5 in their six games.

The Rebels are averaging 8.11 yards per play, which is good for second in college football. Dart will prioritize getting the ball in the hands of running back Henry Parrish Jr. and wide receiver Tre Harris. Parrish Jr. has 570 rushing yards and nine touchdowns through six games. Harris is already closing in on 1,000 yards receiving as he has 885 heading into Saturday with five touchdowns.

Let’s run it back 🍿#BeatLSU | #HottyToddy pic.twitter.com/3GMxpZTott

— Ole Miss Football (@OleMissFB) October 10, 2024

Ole Miss’s defense has also been strong. They have yet to allow a team to score more than 20 points in a game. They have been vulnerable through the air, but they rank first in the country in rushing defense. Ole Miss is allowing just 63.7 rush yards per game.

LSU Betting Trends

LSU is 4-1 this season, but they are just 1-4 against the spread. The Tigers have won four in a row after losing their opener to USC in Las Vegas earlier this season. LSU is 2-3 to the over this year.

Garrett Nussmeier has put together a strong start to the season. He has thrown for 1,652 yards, 15 touchdowns, and 4 interceptions. He has plenty of weapons at his disposal, especially wide receiver Kyren Lacy. Lacy is averaging over 70 receiving yards per game and has five touchdowns through five games.

LSU’s defense has improved from last season, mostly because they are blitzing at a higher rate. Last year, they generated zero pressure, but now the Tigers are ranked third in the SEC in sacks and have recovered the third-most fumbles in the conference. Still, there is work to do. LSU ranks last in the SEC in passing yards allowed per game.

Ole Miss vs LSU Prediction

Ole Miss is the better team in this matchup. They have the better offense. They have the better defense. But this is a difficult spot for the Rebels. They have to go on the road for a night game in one of the most difficult places to play in college football. LSU is also fresh off a bye week, while Ole Miss has played six straight games.

When getting playing at home after getting extended rest, Brian Kelly is 15-2 straight up and 12-5 against spread. Under Brian Kelly, LSU is 12-0 straight up at home in night games, and Ole Miss has not beaten LSU in Death Valley since 2008. Under Lane Kiffin, Ole Miss is 0-4 straight up against Top 25 SEC teams on the road.

LSU’s defense will need to generate pressure on Jaxson Dart and force some turnovers to stay in this game. The Tigers’ offense will also be ready for a potential shootout. LSU has one of the best offensive lines in the country, and Nussmeier has only been sacked once. They will be able to move the ball against Ole Miss’s vulnerable secondary.

Give me the home team getting over a field goal in what should be a close and exciting SEC game full of fireworks.

• Ole Miss vs LSU Pick: LSU +3.5 (-115)